For definition of Groups, see Preamble Evaluation.
Supplement 7: (1987) (p. 126)
A. Evidence for carcinogenicity to humans (inadequate)
Six cases of respiratory cancer were reported among workers in two small factories where benzoyl chloride and its chlorinated precursors were produced [ref: 1].
B. Evidence for carcinogenicity to animals (inadequate)
Benzoyl chloride was tested in two sets of experiments by skin application to female mice. A few skin carcinomas were observed, but their incidence was not statistically significant [ref: 1].
C. Other relevant data
No data were available on the genetic and related effects of benzoyl chloride in humans. It did not induce mutation or DNA damage in bacteria [ref: 2].
Benzoyl chloride is not classifiable as to its carcinogenicity to humans (Group 3).
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluation: Vol. 71 (1999)
Also see previous evaluation: Vol. 29 (1982)
1. IARC Monographs, 29, 83-91, 1982
2. IARC Monographs, Suppl. 6, 103-104, 1987
See Also: Toxicological Abbreviations Benzoyl chloride (ICSC)