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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

3,3'-DIMETHYLBENZIDINE (o-TOLIDINE)

VOL.: 1 (1972) (p. 87)

CAS No.: 119-93-7

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Purified o-tolidine is a systemic carcinogen in the rat when given subcutaneously. The oral experiment in the rat is of doubtful significance because of the small number of animals involved. In feeding experiments, the commercial product failed to produce tumours in hamsters.

5.2 Human carcinogenicity data

No epidemiological studies are available.

Subsequent evaluation: Suppl. 7 (1987) (p. 62: Group 2B)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 12 March 1998






















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