International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 3 (1973) (p. 241)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Benz(c)acridine produced skin tumours in mice treated topically and bladder
tumours in rats following local paraffin wax pellet implantation. It
has not been tested in other species or by other routes.
5.2 Human carcinogenicity data
No case reports or epidemiological studies on the significance of
benz(c)acridine exposure to man are available. However, coal-tar and other
materials which are known to be carcinogenic to man may contain
benz(c)acridine. The substance has also been detected in other environmental
situations. The possible contribution of heterocyclic compounds from
some environmental sources to the overall carcinogenic risk to man is
discussed in the General Remarks.
Subsequent evaluation: Vol. 32 (1983); Suppl. 7 (1987) (p. 58: Group 3)
For definition of Groups, see Preamble Evaluation.
Last updated: 16 March 1998