International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 3 (1973) (p. 207)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Carcinogenic effects of dibenzo(a,h)pyrene were demonstrated following repeated
skin painting in mice and injections in mice and rats. In the skin
painting experiment, it was less active than benzo(a)pyrene. It has
not been tested by other routes or in other species.
5.2 Human carcinogenicity data
No case reports or epidemiological studies on the significance of
dibenzo(a,h)pyrene exposure to man are available. However, coal-tar and other
materials which are known to be carcinogenic to man may contain
dibenzo(a,h)pyrene. The substance has also been detected in other environmental
situations. The possible contribution of polycyclic aromatic
hydrocarbons from some environmental sources to the overall
carcinogenic risk to man is discussed in the General Remarks.
Subsequent evaluations: Vol. 32 (1983); Suppl. 7 (1987) (p. 62: Group 2B)
For definition of Groups, see Preamble Evaluation.
Last updated: 16 March 1998