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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

N-METHYL-N'-NITRO-N-NITROSOGUANIDINE

VOL.: 4 (1974) (p. 183)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

N-Methyl-N'-nitro-N-nitrosoguanidine (MNNG) is carcinogenic in all species tested: mouse, rat, hamster, rabbit and dog. It has a predominantly local carcinogenic effect following administration by oral and other routes. It is carcinogenic in single-dose experiments.

5.2 Human carcinogenicity data

No epidemiological data are available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987)


Last updated: 17 March 1998






















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