International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 4 (1974) (p. 197)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
N-Nitroso-di-n-butylamine (DBNA) is carcinogenic in all animal species
tested: mouse, rat, hamster and guinea pig. It is carcinogenic by oral
and other routes, and it is particularly effective as a bladder
carcinogen after subcutaneous injection. It is carcinogenic after
exposure to a single dose.
5.2 Human carcinogenicity data
No epidemiological data are available to the Working Group.
Subsequent evaluations: Vol. 17 (1978);
Suppl. 7 (1987) (p. 67: Group 2B)
For definition of Groups, see Preamble Evaluation.
Last updated: 17 March 1998