International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 5 (1974) (p. 211)
CAS No.: 82-68-8
Chem. Abstr. Name: Pentachloronitrobenzene
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Quintozene (pentachloronitrobenzene) was tested in a preliminary study
by the oral route in two strains of mice and produced an increased
incidence of hepatomas in males of one strain. A feeding study in rats
was considered inadequate. Application of quintozene followed by
croton oil to mouse skin gave positive results which could not be
interpreted due to a lack of adequate controls.
5.2 Human carcinogenicity data
No epidemiological studies were available to the Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 71: Group 3)
For definition of Groups, see Preamble Evaluation.
Last updated: 17 March 1998