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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

2-(2-FORMYLHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE

VOL.: 7 (1974) (p. 151)

CAS No.: 3570-75-0

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole is carcinogenic in mice, rats and hamsters following oral administration, the only species and route tested. In mice it produced mainly stomach and pulmonary tumours and lymphocytic leukaemias. In rats it produced mainly mammary, renal, hepatic and gastrointestinal tract tumours and lymphocytic leukaemias; in hamsters it produced mainly forestomach and urinary bladder tumours.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 2B)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 19 March 1998






















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