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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

5-(MORPHOLINOMETHYL)-3-[(5-NITROFURFURYLIDENE)-
AMINO]-2-OXAZOLIDINONE

VOL.: 7 (1974) (p. 161)

dl-Form
CAS No.: 139-91-3

l-Form
CAS No.: 3795-88-8

dl-Form hydrochloride
CAS No.: 13146-28-6

4. Comments on Data Reported and Evaluation

5.1 Animal carcinogenicity data

5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone is carcinogenic in rats following oral administration of its hydrochloride. It produced mainly mammary carcinomas and lymphoblastic lymphomas. No other species or routes of administration were tested.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)

For definition of Groups, see Preamble Evaluation.

Synonyms for the dl-Form


Last updated: 19 March 1998






















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       Toxicological Abbreviations