International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 7 (1974) (p. 203)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Benzene has been tested only in mice by subcutaneous injection and
skin application. The data reported do not permit the conclusion that
carcinogenic activity has been demonstrated.
5.2 Human carcinogenicity data
It is established that exposure to commercial benzene or
benzene-containing mixtures may result in damage to the haematopoietic
system. A relationship between such exposure and the development of
leukaemia is suggested by many case reports, and this suggestion is
strengthened by a case-control study from Japan.
Subsequent evaluation: Vol. 29 (1982);
Suppl. 7 (1987)
Last updated: 19 March 1998