International Agency for Research on Cancer (IARC) - Summaries & Evaluations
POLYCHLORINATED BIPHENYLS (PCBs)
VOL.: 7 (1974) (p. 261)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
A limited number of PCBs have been tested. Kanechlor 500 and Aroclor
1254 are carcinogenic in mice inducing benign and malignant liver-cell
tumours following oral administration, the only route tested. In rats,
Kanechlor 500, 400 and 300 induced multiple hyperplastic liver nodules
following oral administration.
5.2 Human carcinogenicity data
In the absence of epidemiological studies the available case report
does not allow an evaluation to be made.
Subsequent evaluations: Vol. 18 (1978);
Suppl. 7 (1987)
Last updated: 19 March 1998