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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

EVANS BLUE

VOL.: 8 (1975) (p. 151)

CAS No.: 314-13-6
Chem. Abstr. Name: 6,6'-[3,3'-Dimethyl(l,l-biphenyl)-4,4'-diyl]bis(azo)-bis-
(4-amino-5-hydroxy)-1,3-naphthalenedisulfonic acid, tetrasodiun salt

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Evans blue was carcinogenic in one study in rats when administered intraperitoneally, the only species and route tested. It produced sarcomas of the reticuloendothelial system in the liver.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 21 March 1998






















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