International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 8 (1975) (p. 233)

CAS No.: 3118-97-6
Chem. Abstr. Name: 1-[(2,4-Dimethylphenyl)azo]-2-naphthalenol

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Sudan II was tested in mice and rats by the oral and subcutaneous routes. Results of these studies cannot be evaluated because of the inadequacy either of the number of animals used, the duration of the experiment or the degree of reporting.

Sudan II was also tested in mice by bladder implantation, resulting in a high incidence of bladder carcinomas (see also General Remarks).

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 72: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 21 March 1998

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