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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

SUNSET YELLOW FCF

VOL.: 8 (1975) (p. 257)

CAS No.: 2783-94-0
Chem. Abstr. Name: 6-Hydroxy-5-[(4-sulfophenyl)azo]-2- naphthalenesulfonic acid, disodium salt

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

The Working Group considered tests in which sunset yellow FCF was administered to mice and rats by the oral route and to rats by the subcutaneous route. In the oral experiments in mice there was no evidence of carcinogenicity as compared with controls. Tests in rats by the oral route showed negative results, but the experiments were inadequately reported. Repeated subcutaneous injections in rats led to neither local nor distant tumours.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 72: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 21 March 1998






















    See Also:
       Toxicological Abbreviations
       Sunset Yellow FCF (WHO Food Additives Series 17)
       SUNSET YELLOW FCF (JECFA Evaluation)