International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 10 (1976) (p. 275)
CAS No.: 6870-67-3
Chem. Abstr. Name: (15a,20R)15,20-Epoxy-15,20-dihydro-12-hydroxy-senecionan-11,16-dione
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
No data were available concerning the carcinogenicity of pure
jacobine. However, see also the section "General Information and
Conclusions on Pyrrolizidine Alkaloids" in this volume.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Subsequent evaluation: Suppl. 7 (1987) (p. 65: Group 3)
For definition of Groups, see Preamble Evaluation.
- NSC 89936
- Stereoisomer of 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3,5,6-trimethyl-
Last updated: 22 March 1998