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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

MITOMYCIN C

VOL.: 10 (1976) (p. 171)

CAS No.: 50-07-7
Chem. Abstr. Name: [1aR-(1aa,8b, 8aa, 8ba)]-6-Amino-8-{[(aminocarbonyl)oxy]methy}-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a ]indole-4,7-dione

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Mitomycin C is carcinogenic in mice following its subcutaneous injection and in rats following its intraperitoneal or intravenous injection. In rats it produced both local and distant tumours.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 22 March 1998






















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       Toxicological Abbreviations