International Agency for Research on Cancer (IARC) - Summaries & Evaluations
RIDDELLIINE
VOL.: 10 (1976) (p. 313)
CAS No.: 23246-96-0
Chem. Abstr. Name: 13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
The available information is insufficient to evaluate the
carcinogenicity of riddelliine. However, see also the section "General
Information and Conclusions on Pyrrolizidine Alkaloids", in this volume.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 71: Group 3)
For definition of Groups, see Preamble Evaluation.
Synonyms
- trans-15-Ethylidene-12b-hydroxy-12a-
hydroxymethyl-13-methylenesenec-1-enine
- Riddelline
- Stereoisomer of 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-
decahydro-6-
hydroxy-6-(hydroxymethyl)-5-methylene(1,6)-dioxacyclododecino[2,3,4-gh]-
pyrrolizidine-2,7-dione
Last updated: 22 March 1998