IPCS INCHEM Home

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

DIALLATE

VOL.: 12 (1976) (p. 69)

CAS No.: 2303-16-4
Chem. Abstr. Name: Bis(l-methylethyl) carbamothioic acid, S-(2,3-dichloro-2-propenyl)ester

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Diallate is carcinogenic in mice after its oral administration: it produced an increased incidence of liver-cell tumours in males of two strains and a slight increase in the number of liver-cell tumours in females of one strain. A single subcutaneous injection in mice produced a slight increase in the incidence of systemic reticulum-cell sarcomas in males of one strain.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Vol. 30 (1983); Suppl. 7 (1987) (p. 61: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998






















    See Also:
       Toxicological Abbreviations