International Agency for Research on Cancer (IARC) - Summaries & Evaluations
METHYL CARBAMATE
VOL.: 12 (1976) (p. 151)
CAS No.: 598-55-0
Chem. Abstr. Name: Carbamic acid, methyl ester
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Methyl carbamate has been tested for skin and lung tumour induction in
mice by subcutaneous and intraperitoneal administration and by skin
application. Although no significant carcinogenic effect was observed,
no evaluation of carcinogenicity can be made due to the short duration
of these experiments. It must be pointed out that in parallel
experiments the related chemical, urethane, was carcinogenic
(IARC, 1974 - Volume 7).
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 66: Group 3)
For definition of Groups, see Preamble Evaluation.
Synonyms
- Methylurethan
- Methylurethane
- Urethylane
Last updated: 25 March 1998