International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 13 (1977) (p. 123)
CAS No.: 61-57-4
Chem. Abstr. Name: 1-(5-Nitro-2-thiazolyl)-2-imidazolidinone
5. Summary of Data Reported and Evaluation
5.1 Animal data
Niridazole is carcinogenic in mice and hamsters after its oral
administration: in mice it induced lymphomas and tumours of the lung,
stomach, mammary gland, ovary and bladder; in hamsters it produced
tumours of the forestomach and papillomas of the urinary bladder.
Infection of treated mice and hamsters with Schistosoma mansoni
cercariae did not affect the carcinogenicity of the compound.
5.2 Human data
No case reports or epidemiological studies were available to the
Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)
For definition of Groups, see Preamble Evaluation.
- Ba 32644
- Ciba 32644-Ba
Last updated: 25 March 1998