International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 15 (1977) (p. 149)
CAS No.: 110-57-6
Chem. Abstr. Name: (E)-1,4-Dichloro-2-butene
5. Summary of Data Reported and Evaluation
5.1 Animal data
trans-1,4-Dichlorobutene has been tested in female mice by skin
application and by subcutaneous and intraperitoneal injection. When
injected subcutaneously or intraperitoneally, it produced low
incidences of local sarcomas. The available data do not allow
an evaluation of the carcinogenicity of this compound to be made.
5.2 Human data
No case reports or epidemiological studies were available to the
Subsequent evaluation: Vol. 71 (1999)
For definition of Groups, see Preamble Evaluation.
Last updated: 13 April 1999