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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

2,5-XYLIDINE (HYDROCHLORIDE)

VOL.: 16 (1978) (p. 377)

2,5-Xylidine
CAS No.: 95-78-3
Chem. Abstr. Name: 2,5-Dimethylbenzenamine

2,5-Xylidine hydrochloride
CAS No.: 51786-53-9
Chem. Abstr. Name: 2,5-Dimethylbenzenamine hydrochloride

5. Summary of Data Reported and Evaluation

5.1 Animal data

Data reported in an abstract indicate that 2,5-xylidine produced an increased incidence of subcutaneous and liver tumours in rats following its oral administration. The inadequacy of the reporting does not allow an evaluation of the carcinogenicity of this compound to be made.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 74: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms for 2,5-Xylidine

Synonyms for 2,5-Xylidine hydrochloride


Last updated: 26 March 1998






















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       Toxicological Abbreviations