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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

GUINEA GREEN B

VOL.: 16 (1978) (p. 199)

CAS No.: 4680-78-8
Chem. Abstr. Name: N-Ethyl-N-(4-[(4-{ethyl[(3-sulfophenyl)methyl]- amino}phenyl)phenyl-
methylene]-2,5-cyclohexadien-1-ylidene)-3- sulfobenzenemethanaminium hydroxide inner salt, sodium salt

5. Summary of Data Reported and Evaluation

5.1 Animal data

Guinea green B has been tested in mice and rats by oral administration and in rats by ambient exposure and subcutaneous injection. It was carcinogenic in rats, producing hepatic tumours after its oral administration, local sarcomas after its subcutaneous injection and benign mammary tumours following ambient exposure.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 64: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 26 March 1998






















    See Also:
       Toxicological Abbreviations
       GUINEA GREEN B (JECFA Evaluation)