International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 17 (1978) (p. 221)
CAS No.: 10595-95-6
Chem. Abstr. Name: N-Methyl-N-nitroso-ethamine
5. Summary of Data Reported and Evaluation
5.1 Experimental data
N-Nitrosomethylethylamine is carcinogenic in rats after its oral
administration, the only species and route tested: it produces
5.2 Human data
No case reports or epidemiological studies were available to the
Working Group. Available information on occurrence suggests that the
general population may be exposed sporadically to low levels of
N-nitrosomethylethylamine; however, no exposed group suitable for an
epidemiological investigation has yet been identified. Reports suggest
that tobacco smokers way be exposed to N-nitrosomthylethylamine
together with other N-nitroso compounds.
There is sufficient evidence of a carcinogenic effect of
N-nitrosomethylethylamine in one experimental animal species. No
epidemiological data were available.
Subsequent evaluation: Suppl. 7 (1987) (p. 68: Group 2B)
For definition of terms, see Preamble Evaluation.
Last updated: 27 March 1998