VOL.: 30 (1983) (p. 283)
Chem. Abstr. Name: Carbamodithioic acid, diethyl-, 2-chloro-2-propenyl ester
No data were available to evaluate the teratogenicity of sulfallate to experimental animals.
Sulfallate was mutagenic to Salmonella typhimurium in the presence of exogenous metabolic activation and to Aspergillus and Streptomyces but not to Saccharomyces cerevisiae with or without metabolic activation. There is sufficient evidence for the mutagenicity of sulfallate in bacterial systems but insufficient evidence for its mutagenicity in mammalian cells or in mammals.
No data were available to evaluate the teratogenic or chromosomal effects of sulfallate in humans.
No case report or epidemiological study of the carcinogenicity of sulfallate alone was available to the Working Group. (See also the section 'Cancer Epidemiology of Pesticide Manufacturers, Formulators and Users', in this volume.)
There is sufficient evidence that sulfallate is carcinogenic to experimental animals.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluation: Suppl. 7 (1987) (p. 72: Group 2B)
See Also: Toxicological Abbreviations