International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 32 (1983) (p. 123)
CAS No.: 225-11-6
Chem. Abstr. Name: Benz(a)acridine
5. Summary of Data Reported and Evaluation
5.1 Experimental data
Benz[a]acridine was inadequately tested for carcinogenicity in
one experiment by skin application to mice.
No data on the teratogenicity of this compound were available.
The single report of the mutagenicity of benz[a]acridine in
Salmonella typhimurium was inconclusive.
There is inadequate evidence that benz[a]acridine is active in
5.2 Human data
Benz[a]acridine is present as a minor component of the total
content of polynuclear aromatic compounds in the environment. Human
exposure to benz[a]acridine occurs primarily through inhalation of
polluted air and by ingestion of food and water contaminated with
The available data are inadequate to permit the evaluation of the
carcinogenicity of benz[a]acridine in experimental animals.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluation: Suppl. 7 (1987) (p. 58: Group 3)
Last updated: 17 April 1998