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2,4-D
ICSC: 0033
Peer-Review Status: 19.10.2005 Validated
2,4-Dichlorophenoxyacetic acid
2,4-D acid 
CAS #: 94-75-7 RTECS #: AG6825000
UN #: 3077
EC #: 607-039-00-8
EINECS #: 202-361-1
 		    Formula: C8H6Cl2O3 / Cl2C6H3OCH2COOH
Molecular mass: 221.0

TYPES OF
HAZARD /
EXPOSURE 		ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO contact with oxidizing agents.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Headache. Nausea. Weakness. Cough. Sore throat.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Diarrhoea. Headache. Nausea. Vomiting. Weakness. Unconsciousness.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
 		PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered , plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: Xn; R: 22-37-41-43-52/53; S: (2)-24/25-26-36/37/39-46-61 
UN Classification
UN Hazard Class: 9; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-90GM7-III.  Store in an area without drain or sewer access. Separated from strong oxidants and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS OR WHITE POWDER. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic fumes including hydrogen chloride. Reacts with strong oxidants. This generates fire and explosion hazard. Attacks some forms of coating and metals. 

Occupational exposure limits
TLV: 10mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2005).
MAK (inhalable fraction): 1 mg/m³; Peak limitation category: II(8); Pregnancy risk group: C; Skin absorption (H); (DFG 2003). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is irritating to the skin, respiratory tract and eyes. Exposure at high levels could cause effects on the nervous system. 

Effects of long-term or repeated exposure
See Notes. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes
Melting point: 140°C
Relative density (water = 1): 0.7-0.8
Solubility in water, g/100ml at 25°C: 0.031 (very poor)
Vapour pressure, Pa at 25°C: 0.01 (negligible)
Octanol/water partition coefficient as log Pow: 2.81   		The substance is harmful to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
2,4-D is a chlorophenoxy-herbicide which, as a group, has been classified by IARC (1987) as possibly carcinogenic to humans, but the data on this specific substance are inconclusive.
Carrier solvents used in commercial formulations may change physical and toxicological properties. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety 		WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information. 
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       Toxicological Abbreviations