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ETHYLENE GLYCOL MONOETHYL ETHER
ICSC: 0060
Peer-Review Status: 05.08.2003 Validated
2-Ethoxyethanol
Monoethyl glycol ether
Oxitol
EGEE
Cellosolve 
CAS #: 110-80-5 RTECS #: KK8050000
UN #: 1171
EC #: 603-012-00-X
EINECS #: 203-804-1
    Formula: C4H10O2 / CH3CH2OCH2CH2OH
Molecular mass: 90.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 44°C explosive vapour/air mixtures may be formed.  Above 44°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID EXPOSURE OF (PREGNANT) WOMEN! STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Drowsiness. Headache. Shortness of breath. Sore throat. Weakness. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Blurred vision. Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Nausea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.  Airtight.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T; R: 60-61-10-20/21/22; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-III.
NFPA Code: H2; F2; R0. 
Fireproof. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OILY LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
The substance can form explosive peroxides. Reacts with strong oxidants. This generates fire and explosion hazard. Attacks many plastics and rubber. 

Occupational exposure limits
TLV: 5ppm as TWA; (skin); BEI issued; (ACGIH 2008).
MAK (sum of concentrations in air of ethylene glycol monoethyl ether and its acetate): 2 ppm, 7.5 mg/m³; Peak limitation category: II(8); Pregnancy risk group: B; Skin absorption (H); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is mildly irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system, blood, bone marrow, kidneys and liver. Exposure at high levels could cause unconsciousness. Medical observation is indicated. 

Effects of long-term or repeated exposure
The liquid defats the skin. The substance may have effects on the blood and bone marrow. This may result in anaemia and lesions of blood cells. May cause toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 135°C
Melting point: -70°C
Relative density (water = 1): 0.93
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 0.5
Relative vapour density (air = 1): 3.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 44°C c.c.
Auto-ignition temperature: 235°C
Explosive limits, vol% in air: 1.7-15.6 (at 93°C)
Octanol/water partition coefficient as log Pow: -0.540  
 

NOTES
Depending on the degree of exposure, periodic medical examination is indicated.
The odour warning when the exposure limit value is exceeded is insufficient.
Check for peroxides prior to distillation; eliminate if found. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations