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ETHYLENE GLYCOL MONOMETHYL ETHER
ICSC: 0061
Peer-Review Status: 05.08.2003 Validated
2-Methoxyethanol
Monomethyl glycol ether
Methyl oxitol
EGME
Methyl cellosolve 
CAS #: 109-86-4 RTECS #: KL5775000
UN #: 1188
EC #: 603-011-00-4
EINECS #: 203-713-7
    Formula: C3H8O2 / CH3OCH2CH2OH
Molecular mass: 76.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 39°C explosive vapour/air mixtures may be formed.  Above 39°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID EXPOSURE OF (PREGNANT) WOMEN! STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Confusion. Cough. Sore throat. Dizziness. Headache. Nausea. Unconciousness. Vomiting. Weakness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Nausea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.  Airtight.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T; R: 60-61-10-20/21/22; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-III.
NFPA Code: H2; F2; R0. 
Fireproof. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
The substance can form explosive peroxides. Reacts with strong oxidants. This generates fire and explosion hazard. Attacks some forms of plastic and coatings. 

Occupational exposure limits
TLV: 0.1ppm as TWA; (skin); (ACGIH 2008).
MAK (sum of concentrations in air of ethylene glycol monoethyl ether and its acetate): 1 ppm, 3.2 mg/m³; Peak limitation category: II(8); Pregnancy risk group: B; Skin absorption (H); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is mildly irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system, blood, bone marrow, kidneys and liver. Exposure at high levels could cause unconsciousness. Medical observation is indicated. 

Effects of long-term or repeated exposure
The liquid defats the skin. The substance may have effects on the blood and bone marrow. This may result in anaemia and lesions of blood cells. May cause toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 125°C
Melting point: -85°C
Relative density (water = 1): 0.96
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 0.83
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 39°C c.c.
Auto-ignition temperature: 285°C
Explosive limits, vol% in air: 2.3-24.5
Octanol/water partition coefficient as log Pow: -0.503  
 

NOTES
Depending on the degree of exposure, periodic medical examination is indicated.
The odour warning when the exposure limit value is exceeded is insufficient.
Check for peroxides prior to distillation; eliminate if found. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations