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NITROBENZENEICSC: 0065
April 2006
CAS #: 98-95-3
UN #: 1662
EC Number: 202-716-0

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Above 88°C explosive vapour/air mixtures may be formed. Risk of fire and explosion. See Chemical Dangers.  NO open flames.  Above 88°C use a closed system and ventilation.  Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS PREVENTION FIRST AID
Inhalation Headache. Blue lips, fingernails and skin. Blue lips, fingernails and skin. Dizziness. Nausea. Weakness. Confusion. Convulsions. Unconsciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health haz
DANGER
Harmful if swallowed
Toxic in contact with skin or if inhaled
Suspected of causing cancer
Suspected of damaging fertility or the unborn child
May cause damage to blood cells
Harmful to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from combustible substances, reducing agents, strong oxidants, strong acids and food and feedstuffs. Store in an area without drain or sewer access. 
PACKAGING
Do not transport with food and feedstuffs. 
NITROBENZENE ICSC: 0065
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
PALE YELLOW OILY LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
On combustion, forms toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants and reducing agents. This generates fire and explosion hazard. Reacts violently with strong acids and nitrogen oxides. This generates explosion hazard. 

Formula: C6H5NO2
Molecular mass: 123.1
Boiling point: 211°C
Melting point: 5°C
Relative density (water = 1): 1.2
Solubility in water, g/100ml: 0.2
Vapour pressure, Pa at 20°C: 20
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 88°C c.c.
Auto-ignition temperature: 480°C
Explosive limits, vol% in air: 1.8-40
Octanol/water partition coefficient as log Pow: 1.86  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
The substance may cause effects on the blood. This may result in the formation of methaemoglobin. Exposure could cause lowering of consciousness. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
The substance may have effects on the blood, spleen and liver. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 1 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).
MAK: 0.51 mg/m3, 0.1 ppm; peak limitation category: II(4); skin absorption (H); carcinogen category: 4; pregnancy risk group: C.
EU-OEL: 1 mg/m3, 0.2 ppm as TWA; (skin) 

ENVIRONMENT
The substance is harmful to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Use of alcoholic beverages enhances the harmful effect.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 23/24/25-40-48/23/24-51/53-62; S: (1/2)-28-36/37-45-61 

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    See Also:
       Toxicological Abbreviations
       Nitrobenzene (EHC 230, 2003)
       Nitrobenzene (IARC Summary & Evaluation, Volume 65, 1996)