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p-NITROPHENOL
ICSC: 0066
Peer-Review Status: 25.11.1998 Validated
4-Nitrophenol
4-Hydroxynitrobenzene 
CAS #: 100-02-7 RTECS #: SM2275000
UN #: 1663
EC #: 609-015-00-2
EINECS #: 202-811-7
    Formula: C6H5NO3
Molecular mass: 139.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE!   
Inhalation Blue lips, fingernails and skin. Cough. Burning sensation. Confusion. Convulsions. Dizziness. Headache. Nausea. Sore throat. Unconciousness. Weakness.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Sore throat. Vomiting. See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: Xn; R: 20/21/22-33; S: (2)-28 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1663.
NFPA Code: H3; F1; R2. 
Separated from combustible substances, reducing agents and food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-PALE-YELLOW CRYSTALS. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
May explode on heating. Decomposes on heating. This produces toxic fumes including nitrogen oxides. Mixtures with potassium hydroxide are explosive. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at at 279°C°C
Melting point: 111-116°C
Density: 1.5 g/cm³
Solubility in water, g/100ml at 20°C: 1.24
Vapour pressure, Pa at 20°C: 0.0032
Flash point: 169°C
Auto-ignition temperature: 490°C
Octanol/water partition coefficient as log Pow: 1.91  
The substance is toxic to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Card has been partly updated in April 2005.
See section Physical properties. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations