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TETRACHLOROETHYLENE
ICSC: 0076
Peer-Review Status: 12.04.2013 Validated
PER
Ethylene Tetrachloride
PERC
Tetracap
1,1,2,2-tetrachloroethene
1,1,2,2-Tetrachloroethylene
Perchloroethylene
Tetrachloroethene 
CAS #: 127-18-4 RTECS #: KX3850000
UN #: 1897
EC #: 602-028-00-4
EINECS #: 204-825-9
    Formula: C2Cl4 / Cl2C=CCl2
Molecular mass: 165.8

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with hot surfaces or finely divided metals.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION Risk of fire and explosion on contact with metals. See Chemical Dangers.  NO contact with metals. See Chemical Dangers   
 
EXPOSURE   STRICT HYGIENE! PREVENT GENERATION OF MISTS!   
Inhalation Cough. Dizziness. Headache. Drowsiness. Nausea. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin Dry skin. Redness. Burning sensation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Burning sensation. Pain.  Wear safety goggles or face shield.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Sore throat. Aspiration hazard! See Inhalation. Cardiac dysrhythmia. Respiratory arrest.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance and complete protective clothing. Ventilation. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: Xn, N; R: 40-51/53; S: (2)-23-36/37-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Warning
Causes skin irritation
Suspected of causing cancer
May be harmful if swallowed and enters airways
May cause drowsiness or dizziness
Toxic to aquatic life with long lasting effects 
excl mark;warncancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F0; R0.  Separated from metals, ignition sources and food and feedstuffs. See Chemical Dangers. Keep in the dark. Keep in a well-ventilated room. Dry. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes of hydrogen chloride, phosgene and chlorine. Decomposes slowly on contact with moisture. This produces trichloroacetic acid and hydrochloric acid. Reacts violently with finely divided metals. This generates fire and explosion hazard. 

Occupational exposure limits
TLV: 25 ppm, 170 mg/m³ as TWA; 100 ppm, 685 mg/m³ as STEL; A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2009).
MAK: Carcinogen category: 3B; Skin absorption (H); (DFG 2004).
EU OEL (N selected): SCOEL recommendation available.
EU OEL ( selected): 20 ppm as TWA; 40 ppm as STEL; SCOEL recommendation available. 

Routes of exposure
The substance can be absorbed into the body by inhalation, by ingestion and through the skin. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. The substance may cause effects on the central nervous system. Exposure at high levels could cause unconsciousness. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver, kidneys and central nervous system. This substance is probably carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 121°C
Melting point: -22°C
Density (at 20°C): 1.62 g/cm³
Solubility in water, g/100ml at 20°C: 0.015
Vapour pressure, kPa at 20°C: 1.9
Relative vapour density (air = 1): 5.7
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.09
Octanol/water partition coefficient as log Pow: 3.4
Auto-ignition temperature: > 650°C  
The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Use of alcoholic beverages enhances the harmful effect. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Tetrachloroethylene (EHC 31, 1984)
       Tetrachloroethylene (HSG 10, 1987)
       TETRACHLOROETHYLENE (JECFA Evaluation)
       Tetrachloroethylene (UKPID)
       Tetrachloroethylene (IARC Summary & Evaluation, Volume 63, 1995)