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ACETONE ICSC: 0087
Date of Peer Review: April 2009

2-Propanone
Dimethyl ketone
Methyl ketone
CAS # 67-64-1 C3H6O / CH3-CO-CH3
RTECS # AL3150000 Molecular mass: 58.1
UN # 1090
EC Annex 1 Index # 606-001-00-8
EC/EINECS # 200-662-2
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Highly flammable.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water in large amounts, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE


Inhalation Sore throat. Cough. Confusion. Headache. Dizziness. Drowsiness. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin Dry skin.
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Blurred vision.
Safety spectacles
Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Ingestion Nausea. Vomiting. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Remove all ignition sources. Ventilation. Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Then wash away with plenty of water.

EMERGENCY RESPONSE STORAGE
NFPA Code: H 1; F 3; R 0;
Fireproof. Separated from : see Chemical Dangers. Store in an area without drain or sewer access.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
ACETONE ICSC: 0087
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance can form explosive peroxides on contact with strong oxidants such as acetic acid, nitric acid, hydrogen peroxide. Reacts with chloroform and bromoform under basic conditions, causing fire and explosion hazard. Attacks plastic.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 500 ppm as TWA, 750 ppm as STEL; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2009).
EU OEL: 500 ppm, 1210 mg/m³ as TWA (EU 2000).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C ; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes and the respiratory tract. Exposure at high levels may result in lowering of consciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin. Repeated contact with skin may cause dryness and cracking.
PHYSICAL PROPERTIES
Boiling point: 56°C
Melting point: -95°C
Relative density (water = 1): 0.8
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 24
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: -18°C c.c.
Auto-ignition temperature: 465°C
Explosive limits, vol% in air: 2.2-13
Octanol/water partition coefficient as log Pow: -0.24
Viscosity, mm^2/s at 40 °C: 0.34
ENVIRONMENTAL DATA

NOTES
Use of alcoholic beverages enhances the harmful effect.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
© IPCS, CEC 2005
    See Also:
       Toxicological Abbreviations
       Acetone (EHC 207, 1998)
       Acetone (FAO Nutrition Meetings Report Series 48a)
       ACETONE (JECFA Evaluation)
       Acetone  (SIDS)