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ETHYLENEIMINE
ICSC: 0100
Peer-Review Status: 10.07.2002 Validated
Aziridine
Azacyclopropane
Dihydro-1H-azirine 
CAS #: 151-56-4 RTECS #: KX5075000
UN #: 1185
EC #: 613-001-00-1
EINECS #: 205-793-9
    Formula: C2H5N / CH2NHCH2
Molecular mass: 43.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with acids.  Use water in large amounts, alcohol-resistant foam, powder. NO carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion on contact with acids or oxidizing agents.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Dizziness. Headache. Laboured breathing. Nausea. Vomiting. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Skin burns. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Vomiting. Shock or collapse. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Remove all ignition sources. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: F, T+, N; R: 45-46-11-26/27/28-34-51/53; S: 53-45-61; Note: D, E 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTF-1.
NFPA Code: H3; F3; R3. 
Fireproof. Separated from acids, oxidants and food and feedstuffs. Dry. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
The substance may polymerize under the influence of acids and oxidizing materials. This generates fire or explosion hazard. On combustion, forms toxic and corrosive fumes including nitrogen oxides. The substance is a medium strong base. 

Occupational exposure limits
TLV: 0.5ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2002).
MAK: Carcinogen category: 2; Germ cell mutagen group: 3A; Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of of the vapour may cause lung oedema. See Notes. The substance may cause effects on the central nervous system, kidneys and liver. Exposure far above the OEL could cause death. The effects may be delayed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. This substance is possibly carcinogenic to humans. May cause heritable genetic damage to human germ cells. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 56-57°C
Melting point: -74°C
Relative density (water = 1): 0.8
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 21.3
Relative vapour density (air = 1): 1.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: -11°C c.c.
Auto-ignition temperature: 322°C
Explosive limits, vol% in air: 3.3-55
Octanol/water partition coefficient as log Pow: -0.36  
The substance is harmful to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is indicated.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
The odour warning when the exposure limit value is exceeded is insufficient.
Ethyleneimine vapours are uninhibited and may form polymers in vents or flame arrestors causing stoppage of vents.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations