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CAPROLACTAM
ICSC: 0118
Peer-Review Status: 25.11.2009 Validated
Hexahydro-2H-azepin-2-one
Aminocaproic lactam
epsilon-Caprolactam 
CAS #: 105-60-2 RTECS #: CM3675000
EC #: 613-069-00-2
EINECS #: 203-313-2
    Formula: C6H11NO
Molecular mass: 113.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use foam, powder, carbon dioxide, water in large amounts. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough. Abdominal cramps. Dizziness. Headache. Confusion.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion Nausea. Vomiting. Abdominal pain. Diarrhoea.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Let solidify. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.   
EC Classification
Symbol: Xn; R: 20/22-36/37/38; S: (2) 
UN Classification
 
GHS Classification
Signal: Warning
Harmful if swallowed
Causes skin irritation
Causes eye irritation
May cause drowsiness or dizziness 
excl mark;warn

EMERGENCY RESPONSE SAFE STORAGE
  Separated from strong oxidants. Dry. 

IMPORTANT DATA
Physical State; Appearance
WHITE HYGROSCOPIC CRYSTALS OR FLAKES. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides and ammonia. Reacts violently with strong oxidants. This produces toxic fumes. 

Occupational exposure limits
TLV (inhalable vapor and aerosol): 5mg/m³ as TWA; A5 (not suspected as a human carcinogen); (ACGIH 2009).
MAK (inhalable fraction as vapour and dust): 5 mg/m³; Peak limitation category: I(2); Pregnancy risk group: C; (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the skin, eyes and respiratory tract. The substance may cause effects on the central nervous system. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the nervous system and liver. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 267°C
Melting point: 70°C
Relative density (water = 1): 1.02
Solubility in water: good
Vapour pressure, Pa at 25°C: 0.26
Relative vapour density (air = 1): 3.91
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0
Flash point: 125°C o.c.
Auto-ignition temperature: 375°C
Explosive limits, vol% in air: 1.4-8
Octanol/water partition coefficient as log Pow: -0.19  
This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
The substance is usually used, stored and transported in liquefied (molten) form at about 80°C. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Caprolactam  (SIDS)
       Caprolactam (IARC Summary & Evaluation, Volume 71, 1999)