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CAPTAFOL
ICSC: 0119
Peer-Review Status: 26.11.2009 Validated
N-(1,1,2,2-Tetrachloroethylthio)cyclohex-4-ene-1,2-dicarboximide
3a,4,7,7a-Tetrahydro-N-(1,1,2,2-tetrachloroethanesulphenyl)phthalimide 
CAS #: 2425-06-1 RTECS #: GW4900000
EC #: 613-046-00-7
EINECS #: 219-363-3
    Formula: C10H9Cl4NO2S
Molecular mass: 349.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Sore throat. Wheezing. Shortness of breath.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Rash. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Itching.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion Burning sensation. Abdominal pain.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 45-43-50/53; S: 53-45-60-61 
UN Classification
 
GHS Classification
Signal: Danger
Causes eye irritation
Causes skin irritation
May cause allergic or asthmatic symptoms or breathing difficulties if inhaled
May cause an allergic skin reaction
May cause cancer
May cause respiratory irritation
Very toxic to aquatic life 
excl mark;warncancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Provision to contain effluent from fire extinguishing. Separated from strong bases and food and feedstuffs. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALLINE POWDER. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163), nitrogen oxides and sulfur oxides. Attacks metals. 

Occupational exposure limits
TLV: 0.1mg/m³ as TWA; (skin); A4 (not classifiable as a human carcinogen); (ACGIH 2008).
MAK (not established):. 

Routes of exposure
The substance can be absorbed into the body by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization and allergic conjunctivities. Repeated or prolonged inhalation may cause asthma. The substance may have effects on the liver and kidneys. This substance is probably carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 160-161°C
Solubility in water: none
Relative vapour density (air = 1): 12
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Octanol/water partition coefficient as log Pow: 3.8  
The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Captafol (HSG 49, 1990)
       Captafol (PIM 097)
       Captafol (FAO/PL:1969/M/17/1)
       Captafol (WHO Pesticide Residues Series 3)
       Captafol (WHO Pesticide Residues Series 4)
       Captafol (Pesticide residues in food: 1976 evaluations)
       Captafol (Pesticide residues in food: 1977 evaluations)
       Captafol (IARC Summary & Evaluation, Volume 53, 1991)