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CARBOFURAN
ICSC: 0122
Peer-Review Status: 22.04.2004 Validated
2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
2,2-Dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamate 
CAS #: 1563-66-2 RTECS #: FB9450000
UN #: 2757
EC #: 006-026-00-9
EINECS #: 216-353-0
    Formula: C12H15NO3
Molecular mass: 221

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.     
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Sweating. Pupillary constriction, muscle cramp, excessive salivation. Dizziness. Vomiting. Laboured breathing. Unconciousness.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. See Notes. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes   Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Diarrhoea. Headache. Nausea. Vomiting. Weakness. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T+, N; R: 26/28-50/53; S: (1/2)-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
Fatal if swallowed or if inhaled
Causes damage to central nervous system
Causes damage to the central nervous system through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 
skull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-I.  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides. 

Occupational exposure limits
TLV: 0.1mg/m³ as TWA; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of short-term exposure
The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Cholinesterase inhibition. The effects may be delayed. Exposure could cause death. Medical observation is indicated. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 150°C
Melting point: 153°C
Density: 1.2 g/cm³
Solubility in water, g/100ml at 25°C: 0.07
Vapour pressure, Pa at 33°C: 0.0027
Octanol/water partition coefficient as log Pow: 2.32  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to soil organisms, bees and birds. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Do NOT take working clothes home.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Card has been partially updated in April 2013: see GHS classification. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Carbofuran (Pesticide residues in food: 1979 evaluations)
       Carbofuran (Pesticide residues in food: 1980 evaluations)
       Carbofuran (Pesticide residues in food: 1996 evaluations Part II Toxicological)
       Carbofuran (JMPR Evaluations 2002 Part II Toxicological)