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2-CHLOROACETOPHENONEICSC: 0128
August 2002
CAS #: 532-27-42-Chloro-1-phenylethanone
alpha-Chloroacetophenone
Phenacyl chloride
UN #: 1697
EINECS #: 208-531-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, powder, foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 STRICT HYGIENE!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Burning sensation. Cough. Sore throat. Nausea. Shortness of breath.  Use local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision. Partial loss of vision.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give one or two glasses of water to drink. Give a slurry of activated charcoal in water to drink. Refer for medical attention . Rest. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Sweep spilled substance into covered sealable, plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from food and feedstuffs. Keep in a well-ventilated room. 
PACKAGING
Do not transport with food and feedstuffs. 
2-CHLOROACETOPHENONE ICSC: 0128
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-GREY CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride. 

Formula: C8H7ClO / C6H5COCH2Cl
Molecular mass: 154.6
Boiling point: 244-245°C
Melting point: 54-59°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 25°C: 1.64
Vapour pressure, Pa at 20°C: 0.7
Relative vapour density (air = 1): 5.3
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0
Flash point: 118°C c.c.
Octanol/water partition coefficient as log Pow: 2.08  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Effects of short-term exposure
Lachrymation. The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract. Inhalation of the vapour or aerosol may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. 


Occupational exposure limits
TLV: 0.05 ppm as TWA; A4 (not classifiable as a human carcinogen) 

ENVIRONMENT
 

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations