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DI(2,3-EPOXYPROPYL)ETHER
ICSC: 0145
Peer-Review Status: 10.09.1997 Validated
bis(2,3-Epoxypropyl)ether
Diglycidyl ether
2,2'-(Oxybis(methylene))bis-oxirane
DGE 
CAS #: 2238-07-5 RTECS #: KN2350000
EINECS #: 218-802-6
    Formula: C6H10O3 / C2H3OCH2OCH2C2H3O
Molecular mass: 130.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Above 64°C explosive vapour/air mixtures may be formed.  Above 64°C use a closed system, ventilation and explosion-proof electrical equipment.   
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Dizziness. Shortness of breath. Sore throat. Unconciousness. Weakness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin MAY BE ABSORBED! Dry skin. Redness. Roughness. Skin burns. Pain. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. Vomiting.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.   
EC Classification
 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Separated from strong oxidants. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
The substance can presumably form explosive peroxides. May explode on heating. Reacts with strong oxidants. 

Occupational exposure limits
TLV: 0.1ppm as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: Carcinogen category: 3B; Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is severely irritating to the eyes, skin and respiratory tract. Inhalation of of the vapour may cause lung oedema. See Notes. The substance may cause effects on the blood, kidneys, liver and testes. Exposure could cause lowering of consciousness. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 100kPa: 260°C
Relative density (water = 1): 1.26
Solubility in water: see Notes
Vapour pressure, Pa at 25°C: 12
Relative vapour density (air = 1): 4.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 64°C
Explosive limits, vol% in air: see Notes 
 

NOTES
Solubility in water, melting point, auto-ignition temperature and explosive limits are unknown in literature.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
The odour warning when the exposure limit value is exceeded is insufficient.
Check for peroxides prior to distillation; eliminate if found.
Card has been partly updated in April 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations