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METHYL ETHYL KETONEICSC: 0179
Ethyl methyl ketone
2-Butanone
MEK
Methyl acetone
April 2017
CAS #: 78-93-3
UN #: 1193
EC Number: 201-159-0

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable.  Vapour/air mixtures are explosive.  NO open flames, NO sparks and NO smoking.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  Use alcohol-resistant foam, water, powder, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT GENERATION OF MISTS!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Headache. Dizziness. Nausea. Vomiting. Drowsiness. Numbness. Laboured breathing.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation. Unconsciousness.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

flam;flameexcl mark;warncancer;health haz
DANGER
Highly flammable liquid and vapour
Causes serious eye irritation
May cause respiratory irritation
May cause drowsiness or dizziness
Suspected of damaging fertility or the unborn child
May be harmful if swallowed and enters airways 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: II 

STORAGE
Fireproof. Separated from strong oxidants and strong acids. Cool. Well closed. Store in an area without drain or sewer access. 
PACKAGING
 
METHYL ETHYL KETONE ICSC: 0179
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Reacts violently with strong oxidants and inorganic acids. This generates fire and explosion hazard. Attacks some plastics. 

Formula: C4H8O / CH3COCH2CH3
Molecular mass: 72.1
Boiling point: 80°C
Melting point: -86°C
Relative density (water = 1): 0.8
Solubility in water, g/100ml at 20°C: 29 (good)
Vapour pressure, kPa at 20°C: 10.5
Relative vapour density (air = 1): 2.41
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: -9°C c.c.
Auto-ignition temperature: 505°C
Explosive limits, vol% in air: 1.8-11.5
Octanol/water partition coefficient as log Pow: 0.29
Viscosity: 0.40 cP at 25°C 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, by ingestion and through the skin. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system. Exposure could cause unconsciousness. If swallowed the substance easily enters the airways and could result in aspiration pneumonitis. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
The substance defats the skin, which may cause dryness or cracking. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 200 ppm as TWA; 300 ppm as STEL; BEI issued.
MAK: 600 mg/m3, 200 ppm; peak limitation category: I(1); skin absorption (H); pregnancy risk group: C.
EU-OEL: 600 mg/m3, 200 ppm as TWA; 900 mg/m3, 300 ppm as STEL 

ENVIRONMENT
Avoid release to the environment in circumstances different to normal use. 

NOTES
The odour warning when the exposure limit value is exceeded is insufficient. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, Xi; R: 11-36-66-67; S: (2)-9-16; Note: 6 

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    See Also:
       Toxicological Abbreviations
       Methyl ethyl ketone (EHC 143, 1992)