IPCS INCHEM Home
MONOCROTOPHOSICSC: 0181
November 2016
CAS #: 6923-22-4Dimethyl (E)-1-methyl-2-(methylcarbamoyl) vinyl phosphate
trans-Monocrotophos
(E)-Phosphoric acid dimethyl [1-methyl-3-(methylamino)-3-oxo-1-propenyl] ester
UN #: 2783
EINECS #: 230-042-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  Risk of fire and explosion if formulations contain flammable/explosive solvents.  NO open flames.    Use water spray, dry powder, foam, carbon dioxide.   

 PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! FIRST AID: USE PERSONAL PROTECTION. 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Pupillary constriction, muscle cramp, excessive salivation. Headache. Sweating. Muscle twitching. Weakness. Nausea. Vomiting. Laboured breathing. Unconsciousness. Symptoms may be delayed.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. Wear protective gloves when administering first aid. 
Eyes MAY BE ABSORBED! Redness. Blurred vision. Further see Inhalation.  Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting. Refer immediately for medical attention. See Notes. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable, plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health hazenviro;aqua
DANGER
Fatal if swallowed, in contact with skin or if inhaled
Suspected of causing genetic defects
Causes damage to nervous system
Causes damage to the nervous system through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access. 
PACKAGING
Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
Marine pollutant. 
MONOCROTOPHOS ICSC: 0181
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS HYGROSCOPIC CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and irritating fumes including nitrogen oxides and phosphorus oxides. Attacks iron, steel and brass. 

Formula: C7H14NO5P / (CH3O)2PO-OC(CH3)=CHCO-NHCH3
Molecular mass: 223.2
Boiling point at 0.00007kPa: 125°C
Melting point: 54-55°C
Density (at 20°C): 1.22 g/cm³
Solubility in water, g/100ml at 20°C: 100 (miscible)
Vapour pressure, Pa at 20°C: 0.0003 (negligible)
Octanol/water partition coefficient as log Pow: -0.2 (calculated) 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Medical observation is indicated. Exposure could cause death. The effects may be delayed. See Notes. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


Occupational exposure limits
TLV: 0.05 mg/m3, ppm, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued 

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees, birds and mammals. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
This card applies to trans-monocrotophos.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
CAS 919-44-8 is cis-monocrotophos, and CAS 2157-98-4 is unspecified monocrotophos. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T+, N; R: 24-26/28-50/53-68; S: (1/2)-36/37-45-60-61 

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.
    See Also:
       Toxicological Abbreviations
       Monocrotophos (HSG 80, 1993)
       Monocrotophos (WHO Pesticide Residues Series 2)
       Monocrotophos (WHO Pesticide Residues Series 5)
       Monocrotophos (Pesticide residues in food: 1991 evaluations Part II Toxicology)
       Monocrotophos (Pesticide residues in food: 1993 evaluations Part II Toxicology)
       Monocrotophos (Pesticide residues in food: 1995 evaluations Part II Toxicological & Environmental)