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2-NITROPROPANE
ICSC: 0187
Peer-Review Status: 04.04.2006 Validated
Isonitropropane
Dimethylnitromethane
sec-Nitropropane
2-NP 
CAS #: 79-46-9 RTECS #: TZ5250000
UN #: 2608
EC #: 609-002-00-1
EINECS #: 201-209-1
    Formula: C3H7NO2 / CH3CHNO2CH3
Molecular mass: 89.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 24°C explosive vapour/air mixtures may be formed.  Above 24°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Cough. Dizziness. Drowsiness. Headache. Nausea. Vomiting. Diarrhoea. Weakness. Shortness of breath.  Use ventilation, local exhaust or breathing protection.  Refer for medical attention. 
Skin Dry skin. Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: T; R: 45-10-20/22; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
Signal: Danger
Harmful if swallowed
Harmful if inhaled vapour
Suspected of causing genetic defects
May cause cancer
Causes damage to liver 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-III.
NFPA Code: H1; F3; R2. 
Fireproof. Separated from strong bases, strong acids, amines, powdered metals and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OILY LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. Mixtures with acids, amines, inorganic bases and heavy metal oxides are shock-sensitive. Attacks some forms of plastic, rubber and coatings. 

Occupational exposure limits
TLV: 10ppm (ceiling value); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2005).
MAK: Carcinogen category: 2; Skin absorption (H); (DFG 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is irritating to the eyes and respiratory tract. The substance is mildly irritating to the skin. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause liver impairment and death. 

Effects of long-term or repeated exposure
The liquid defats the skin. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 120°C
Melting point: -91°C
Relative density (water = 1): 0.99
Solubility in water, g/100ml at 25°C: 1.7
Vapour pressure, kPa at 20°C: 1.7
Relative vapour density (air = 1): 3.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 24°C c.c.
Auto-ignition temperature: 428°C
Explosive limits, vol% in air: 2.6-11
Octanol/water partition coefficient as log Pow: 0.93  
 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The odour warning when the exposure limit value is exceeded is insufficient.
NiPar S-20 and NiPar S-30 are trade names.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       2-NITROPROPANE (JECFA Evaluation)