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2-NITROPROPANEICSC: 0187
April 2006
CAS #: 79-46-9Isonitropropane
Dimethylnitromethane
sec-Nitropropane
2-NP
UN #: 2608
EINECS #: 201-209-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.  Above 24°C explosive vapour/air mixtures may be formed.  NO open flames, NO sparks and NO smoking.  Above 24°C use a closed system, ventilation and explosion-proof electrical equipment.  Use water spray, powder, alcohol-resistant foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 

 AVOID ALL CONTACT!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Cough. Dizziness. Drowsiness. Headache. Nausea. Vomiting. Diarrhoea. Weakness. Shortness of breath.  Use ventilation, local exhaust or breathing protection.  Refer for medical attention. 
Skin Dry skin. Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

excl mark;warncancer;health haz
DANGER
Harmful if swallowed or if inhaled
Suspected of causing genetic defects
May cause cancer
Causes damage to liver 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: III 

STORAGE
Fireproof. Separated from strong bases, strong acids, amines, powdered metals and food and feedstuffs. 
PACKAGING
 
2-NITROPROPANE ICSC: 0187
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS OILY LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. Mixtures with acids, amines, inorganic bases and heavy metal oxides are shock-sensitive. Attacks some forms of plastic, rubber and coatings. 

Formula: C3H7NO2 / CH3CHNO2CH3
Molecular mass: 89.1
Boiling point: 120°C
Melting point: -91°C
Relative density (water = 1): 0.99
Solubility in water, g/100ml at 25°C: 1.7
Vapour pressure, kPa at 20°C: 1.7
Relative vapour density (air = 1): 3.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 24°C c.c.
Auto-ignition temperature: 428°C
Explosive limits, vol% in air: 2.6-11
Octanol/water partition coefficient as log Pow: 0.93  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Effects of short-term exposure
The vapour is irritating to the eyes and respiratory tract. The substance is mildly irritating to the skin. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause liver impairment and death. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
The substance defats the skin, which may cause dryness or cracking. This substance is possibly carcinogenic to humans. 


Occupational exposure limits
TLV: 10 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans).
MAK: skin absorption (H); carcinogen category: 2 

ENVIRONMENT
 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T; R: 45-10-20/22; S: 53-45; Note: E 

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    See Also:
       Toxicological Abbreviations
       2-NITROPROPANE (JECFA Evaluation)