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TEMEPHOSICSC: 0199
April 2007
CAS #: 3383-96-8O,O,O',O'-Tetramethyl O,O'-thiodi-p-phenylene bis(phosphorothioate)
O,O'-(Thiodi-4,1-phenylene) bis(O,O-dimethylphosphorothioate)
Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester
UN #: 2783
EINECS #: 222-191-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, foam, powder, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT DISPERSION OF DUST! PREVENT GENERATION OF MISTS!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Dizziness. Nausea. Muscle twitching. Sweating. Pupillary constriction, muscle cramp, excessive salivation. Vomiting. Diarrhoea. Laboured breathing. Convulsions. Unconsciousness.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. 
Eyes Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion Abdominal cramps. See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health hazenviro;aqua
DANGER
Toxic in contact with skin
Harmful if swallowed or if inhaled
Causes damage to nervous system
Very toxic to aquatic life
Very toxic to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 

STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access. 
PACKAGING
Do not transport with food and feedstuffs.
Marine pollutant. 
TEMEPHOS ICSC: 0199
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS OR WHITE CRYSTALS OR LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including phosphorus oxides and sulfur oxides. 

Formula: C16H20O6P2S3
Molecular mass: 466.5
Decomposes at 120-125°C
Melting point: 30°C
Density: 1.3 g/cm³
Solubility in water: none
Vapour pressure at 25°C: negligible
Octanol/water partition coefficient as log Pow: 5.96  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. The effects may be delayed. Medical observation is indicated. Exposure far above the OEL could cause death. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


Occupational exposure limits
TLV: 1 mg/m3, ppm, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued 

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees. Bioaccumulation of this chemical may occur along the food chain. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
The technical grade (90-95%) is a brown, viscous liquid. 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations