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TETRAMETHYL LEAD
ICSC: 0200
Peer-Review Status: 21.04.2005 Validated
Tetramethyl plumbane 
CAS #: 75-74-1 RTECS #: TP4725000
UN #: 1649
EC #: 082-002-00-1
EINECS #: 200-897-0
    Formula: Pb(CH3)4 / C4H12Pb
Molecular mass: 267.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Above 37.8°C explosive vapour/air mixtures may be formed.  Above 37.8°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Convulsions. Dizziness. Headache. Nausea. Unconciousness. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Diarrhoea. Dullness. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T+, N; R: 61-26/27/28-33-62-50/53; S: 53-45-60-61; Note: A, E, 1 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1649.
NFPA Code: H3; F3; R3. 
Fireproof. Separated from strong oxidants, strong acids and food and feedstuffs. Cool. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
May explode on heating above 90°C. Decomposes on burning. This produces toxic fumes including lead and lead oxides. Reacts violently with strong oxidants. Reacts with strong acids. Reacts violently with nitric acid. Attacks rubber. 

Occupational exposure limits
TLV (as Pb): 0.15mg/m³ as TWA; (skin); (ACGIH 2005).
MAK: 0.05 mg/m³; Peak limitation category: II(2); Pregnancy risk group: B; Skin absorption (H); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in brain disorders. The effects may be delayed. Exposure could cause death. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 1.33kPa: 110°C
Melting point: -27.5°C
Relative density (water = 1): 2.0
Solubility in water: none
Vapour pressure, kPa at 20°C: 3.0
Relative vapour density (air = 1): 6.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.23
Flash point: 37.8°C c.c.
Auto-ignition temperature: 254°C
Explosive limits, vol% in air: 1.8-?
Octanol/water partition coefficient as log Pow: 6.2  
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur along the food chain, for example in molluscs and fish. 

NOTES
Commercial products are impure, coloured red, orange or blue, with added stabilizer (1,2-dichloroethane, toluene).
Depending on the degree of exposure, periodic medical examination is suggested.
The relation between odour and the occupational exposure limit cannot be indicated.
Do NOT take working clothes home.
Card has been partly updated in October 2005.
See section EU classification. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations