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ACETYL CHLORIDEICSC: 0210
October 1995
CAS #: 75-36-5Acetic chloride
Ethanoyl chloride
Acetic acid chloride
UN #: 1717
EINECS #: 200-865-6

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.  Vapour/air mixtures are explosive.  NO open flames, NO sparks and NO smoking. NO contact with hot surfaces.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  Use powder, carbon dioxide. NO hydrous agents. NO water.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 

 AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Burning sensation. Cough. Shortness of breath. Sore throat.  Use breathing protection. Use closed system or ventilation.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Dry skin. Redness. Serious skin burns. Burning sensation. Pain. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Cough. Shortness of breath. Sore throat. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II 

STORAGE
Fireproof. Separated from incompatible materials. See Chemical Dangers. Dry. Well closed. 
PACKAGING
Airtight.
Unbreakable packaging.
Put breakable packaging into closed unbreakable container. 
ACETYL CHLORIDE ICSC: 0210
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS FUMING LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts violently with water, alcohols, acids, bases, certain powdered metals and many other compounds. This generates fire and explosion hazard. Attacks many metals in the presence of water. Products of hydrolysis in water include corrosive hydrochloric acid and acetic acid. 

Formula: CH3COCl / C2ClH3O
Molecular mass: 78.5
Boiling point: 51°C
Melting point: -112°C
Relative density (water = 1): 1.11
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 32
Relative vapour density (air = 1): 2.7
Flash point: 5°C c.c.
Auto-ignition temperature: 390°C
Explosive limits, vol% in air: 7.3-19 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Effects of short-term exposure
The vapour is irritating to the eyes and respiratory tract. The substance is corrosive to the eyes and skin. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. See Notes. Exposure could cause unconsciousness. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation of high concentrations may cause effects on the lungs. 


Occupational exposure limits
 

ENVIRONMENT
This substance may be hazardous to the environment. Special attention should be given to water quality. 

NOTES
Reacts violently with fire extinguishing agents such as hydrous agents (water, foam).
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
Do NOT use in the vicinity of a fire or a hot surface, or during welding. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, C; R: 11-14-34; S: (1/2)-9-16-26-45 

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    See Also:
       Toxicological Abbreviations