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ACETYL CHLORIDE
ICSC: 0210
Peer-Review Status: 24.10.1995 Validated
Acetic chloride
Ethanoyl chloride
Acetic acid chloride 
CAS #: 75-36-5 RTECS #: AO6390000
UN #: 1717
EC #: 607-011-00-5
EINECS #: 200-865-6
    Formula: CH3COCl / C2ClH3O
Molecular mass: 78.5

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with hot surfaces.  Use powder, carbon dioxide. NO hydrous agents. NO water. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Burning sensation. Cough. Shortness of breath. Sore throat.  Use breathing protection. Use closed system or ventilation.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Dry skin. Redness. Serious skin burns. Burning sensation. Pain. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Cough. Shortness of breath. Sore throat. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Airtight.
Unbreakable packaging.
Put breakable packaging into closed unbreakable container. 
EC Classification
Symbol: F, C; R: 11-14-34; S: (1/2)-9-16-26-45 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S1717.
NFPA Code: H3; F3; R2; W. 
Fireproof. Separated from incompatible materials. See Chemical Dangers. Dry. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS FUMING LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts violently with water, alcohols, acids, bases, certain powdered metals and many other compounds. This generates fire and explosion hazard. Attacks many metals in the presence of water. Products of hydrolysis in water include corrosive hydrochloric acid and acetic acid. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is irritating to the eyes and respiratory tract. The substance is corrosive to the eyes and skin. Corrosive on ingestion. Inhalation of of the vapour may cause lung oedema. See Notes. Exposure could cause unconsciousness. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation of high concentrations may cause effects on the lungs. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 51°C
Melting point: -112°C
Relative density (water = 1): 1.11
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 32
Relative vapour density (air = 1): 2.7
Flash point: 5°C c.c.
Auto-ignition temperature: 390°C
Explosive limits, vol% in air: 7.3-19 
This substance may be hazardous to the environment. Special attention should be given to water quality. 

NOTES
Reacts violently with fire extinguishing agents such as hydrous agents (water, foam).
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Card has been partly updated in October 2004.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations