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BENZIDINEICSC: 0224
November 2009
CAS #: 92-87-5(1,1'-Biphenyl)-4,4'-diamine
4,4'-Diaminobiphenyl
p-Diaminodiphenyl
Biphenyl-4,4'-ylenediamine
UN #: 1885
EINECS #: 202-199-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, foam, powder, carbon dioxide.   

See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE. AVOID ALL CONTACT!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation   Use closed system and ventilation.  Fresh air, rest. 
Skin MAY BE ABSORBED!  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Wear protective gloves when administering first aid. 
Eyes   Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion   Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

excl mark;warncancer;health hazenviro;aqua
DANGER
Harmful if swallowed
Suspected of causing genetic defects
May cause cancer
Very toxic to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Well closed. Store in an area without drain or sewer access. 
PACKAGING
Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
BENZIDINE ICSC: 0224
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS OR REDDISH CRYSTALLINE POWDER. TURNS DARK ON EXPOSURE TO AIR AND LIGHT. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants, especially nitric acid. 

Formula: C12H12N2 / NH2C6H4-C6H4NH2
Molecular mass: 184.2
Boiling point: 401°C
Melting point: 120°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 25°C: <0.05 (very poor)
Relative vapour density (air = 1): 6.4
Octanol/water partition coefficient as log Pow: 1.34  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Effects of short-term exposure
 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. 

Effects of long-term or repeated exposure
This substance is carcinogenic to humans. 


Occupational exposure limits
TLV: A1 (confirmed human carcinogen); (skin).
MAK: carcinogen category: 1.
MAK skin absorption (H) 

ENVIRONMENT
The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Do NOT take working clothes home.
TLV Note: Exposure by all routes should be carefully controlled to levels as low as possible. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 45-22-50/53; S: 53-45-60-61; Note: E 

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    See Also:
       Toxicological Abbreviations
       Benzidine  (IARC Summary & Evaluation, Supplement7, 1987)
       Benzidine (IARC Summary & Evaluation, Volume 1, 1972)