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bis(CHLOROMETHYL) ETHER
ICSC: 0237
Peer-Review Status: 18.04.2005 Validated
BCME
sym-Dichloromethyl ether
1,1'-Dichlorodimethyl ether
Oxybis(chloromethane)
Chloro(chloromethoxy)methane 
CAS #: 542-88-1 RTECS #: KN1575000
UN #: 2249
EC #: 603-046-00-5
EINECS #: 208-832-8
    Formula: (CH2Cl)2O
Molecular mass: 115

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Burning sensation. Cough. Headache. Laboured breathing. Shortness of breath. Vomiting. Wheezing. Symptoms may be delayed. See Notes.  Use closed system or ventilation.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Burning sensation. Skin burns.  Protective clothing. Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation in the throat and chest. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Airtight.
Special material.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+; R: 45-10-22-24-26; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-20G1TC.
NFPA Code: H4; F0; R0. 
Fireproof. Separated from food and feedstuffs. Dry. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
Decomposes on heating and on contact with water. This produces toxic and corrosive fumes of hydrogen chloride (see ICSC 0163) and formaldehyde. Attacks many metals, plastics and resins. 

Occupational exposure limits
TLV: 0.001ppm as TWA; A1 (confirmed human carcinogen); (ACGIH 2005).
MAK: Carcinogen category: 1; (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of of high concentrations may cause lung oedema. See Notes. The effects may be delayed. Exposure could cause death. 

Effects of long-term or repeated exposure
This substance is carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 104-106°C
Melting point: -42°C
Relative density (water = 1): 1.3
Solubility in water: reaction
Vapour pressure, kPa at 25°C: 3.9
Relative vapour density (air = 1): 4.0
Flash point: <19°C c.c.
Octanol/water partition coefficient as log Pow: 1.05  
 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations