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CYCLOHEXANE
ICSC: 0242
Peer-Review Status: 09.06.2011 Validated
Hexahydrobenzene
Hexamethylene
Hexanaphthene 
CAS #: 110-82-7 RTECS #: GU6300000
UN #: 1145
EC #: 601-017-00-1
EINECS #: 203-806-2
    Formula: C6H12
Molecular mass: 84.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, foam, powder, carbon dioxide. Water may be ineffective. 
EXPLOSION Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools. Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Cough. Nausea. Headache. Dizziness. Weakness. Drowsiness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness. Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness.  Wear safety goggles or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion Abdominal pain. Nausea. Vomiting. Aspiration hazard! Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Remove all ignition sources. Personal protection: self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.   
EC Classification
Symbol: F, Xn, N; R: 11-38-65-67-50/53; S: (2)-9-16-25-33-60-61-62; Note: 4 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
Signal: Danger
Highly flammable liquid and vapour
Causes eye irritation
Causes mild skin irritation
May cause drowsiness and dizziness
May be fatal if swallowed and enters airways
Very toxic to aquatic life with long lasting effects 
flam;flameexcl mark;warncancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H1; F3; R0.  Fireproof. Provision to contain effluent from fire extinguishing. Separated from strong oxidants. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated. 

Chemical dangers
Heating may cause violent combustion or explosion. Reacts with strong oxidants. 

Occupational exposure limits
TLV: 100ppm as TWA; (ACGIH 2010).
EU OEL ( selected): 200ppm, 700mg/m³ as TWA;. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is mildly irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. Exposure could cause lowering of consciousness. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dryness and cracking and dermatitis. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 81°C
Melting point: 7°C
Relative density (water = 1): 0.8
Solubility in water, g/100ml at 25°C: 0.0058 (very poor)
Vapour pressure, kPa at 20°C: 10.3
Relative vapour density (air = 1): 2.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: -18°C c.c.
Auto-ignition temperature: 260°C
Explosive limits, vol% in air: 1.3-8.4
Octanol/water partition coefficient as log Pow: 3.4
Viscosity: 1.26x10-6 mm²/s at 26°C 
The substance is very toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. It is strongly advised not to let the chemical enter into the environment. 

NOTES
The odour warning when the exposure limit value is exceeded is insufficient. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       CYCLOHEXANE (JECFA Evaluation)