IPCS INCHEM Home
1,2-DICHLOROETHANE
ICSC: 0250
Peer-Review Status: 12.04.2013 Validated
Ethylene dichloride
1,2-Ethylene dichloride
Ethane dichloride 
CAS #: 107-06-2 RTECS #: KI0525000
UN #: 1184
EC #: 602-012-00-7
EINECS #: 203-458-1
    Formula: ClCH2CH2Cl / C2H4Cl2
Molecular mass: 98.96

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Sore throat. Nausea. Vomiting. Cough. Headache. Dizziness. Drowsiness. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Administration of oxygen may be needed. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin MAY BE ABSORBED! Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. 
Eyes Redness. Pain.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: F, T; R: 45-11-22-36/37/38; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 6.1; UN Pack Group: II 
GHS Classification
Signal: Danger
Highly flammable liquid and vapour
Harmful if swallowed
May be harmful in contact with skin
Toxic if inhaled
Causes skin and eye irritation
Suspected of causing cancer
Causes damage to lungs, liver and kidneys
May cause drowsiness or dizziness
May cause damage to liver and kidneys through prolonged or repeated exposure
Harmful to aquatic life 
flam;flameskull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F3; R0.  Fireproof. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS VISCOUS LIQUID WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO AIR, MOISTURE AND LIGHT. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated. 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts with alkali metals, powdered metals, ammonia, bases and strong oxidants. This generates fire and explosion hazard. Attacks many metals in the presence of water. 

Occupational exposure limits
TLV: 10ppm as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2012).
MAK: Carcinogen category: 2; Skin absorption (H); (DFG 2012). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is irritating to the eyes, skin and respiratory tract. Inhalation may cause lung oedema. See Notes. The substance may cause effects on the kidneys and liver. This may result in impaired functions, liver damage and kidney damage. Exposure at high concentrations could cause lowering of consciousness and death. The effects may be delayed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver and kidneys, resulting in impaired functions. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 83.5°C
Melting point: -35.7°C
Relative density (water = 1): 1.2
Solubility in water, g/100ml: 0.87
Vapour pressure, kPa at 20°C: 8.7
Relative vapour density (air = 1): 3.42
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: 13°C c.c.
Auto-ignition temperature: 440°C
Explosive limits, vol% in air: 4.2-16
Octanol/water partition coefficient as log Pow: 1.48  
The substance is harmful to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       1,2-DICHLOROETHANE (JECFA Evaluation)
       1,2-Dichloroethane  (SIDS)