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TRIMELLITIC ANHYDRIDE
ICSC: 0345
Peer-Review Status: 22.04.1994 Validated
1,2,4-Benzenetricarboxylic anhydride
1,3-Dihydro-1,3-dioxo-5-isobenzofurancarboxylic acid 
CAS #: 552-30-7 RTECS #: DC2050000
EC #: 607-097-00-4
EINECS #: 209-008-0
    Formula: C9H4O5
Molecular mass: 192.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Prevent build-up of electrostatic charges (e.g., by grounding). Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.   
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE!   
Inhalation Cough. Headache. Nausea. Shortness of breath. Wheezing. Symptoms may be delayed. See Notes.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness. Pain.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. Abdominal pain. Burning sensation. Vomiting. Diarrhoea.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder.   
EC Classification
Symbol: Xn; R: 37-41-42/43; S: (2)-22-26-36/37/39 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Dry. Separated from bases and strong oxidants. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS OR POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc. 

Chemical dangers
Reacts violently with bases and oxidants. Reacts slowly with water. This produces trimellitic acid. 

Occupational exposure limits
TLV: 0.04mg/m³ (ceiling value); (ACGIH 2005).
MAK: 0.04 mg/m³; Peak limitation category: I(1); Sensitization of respiratory tract (SA); (DFG 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract. Inhalation of dust may cause asthma-like reactions. 

Effects of long-term or repeated exposure
Repeated or prolonged inhalation may cause asthma. The substance may cause allergic reactions with flu-like symptoms and 'pulmonary disease-anaemia syndrome'. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 1.87kPa: 240-245°C
Melting point: 161-163.5°C
Solubility in water: reaction
Vapour pressure at 25°C: negligible
Relative vapour density (air = 1): 6.6
Flash point: 227°C o.c. 
 

NOTES
The symptoms of allergic reactions including asthma do not become manifest until 4 to 12 hours.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
The occupational exposure limit value should not be exceeded during any part of the working exposure.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Trimellitic anhydride (HSG 71, 1992)